Calcium-channel blockers: current place in hypertension
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چکیده
منابع مشابه
Calcium channel blockers in primary pulmonary hypertension.
The demonstration that the calcium channel blockers reduce pulmonary vasomotor tone in experimental models of pulmonary hypertension has served as the rationale for their use in the management of primary pulmonary hypertension. The three currently available agents, verapamil, nifedipine, and diltiazem, have varying degrees of pulmonary vasoactivity. Experience with their use is reviewed.
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Wound healing is a natural response to restore the injured tissue to normal. Wound healing is also complicated process involving different cellular, molecular and biochemical mechanisms and various types of cytokines and growth factors. Calcium channel blockers belong to cardiovascular medicine and administrated to treatment of hypertension, angina and cardiac arrhythmia because of vasodilatory...
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The objective of the study was to evaluate the antiglaucoma effect of calcium channel blockers diltiazem and verapamil. Albino rabbits were used and chronic glaucoma was induced in them using freshly prepared 150 units of alphachymotrypsin. 0.1 mL of drug solution was administered topically into the left eye whereas the right served as control. The pressure recording was carried out at 15, 30, ...
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Go to www.pharmacist.com and take your test online for instant credit. Objectives: To describe for pharmacists the basics of hypertension with a specific emphasis on the role of calcium channel blockers in the management of this condition. Data sources: Published literature on hypertension identified via a search of PubMed and pertinent government Web sites. Data synthesis: Hypertension affects...
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In 1964, Albretch Fleckenstein described an inhibitory action ofverapamil and prenylamine on excitation-contraction coupling that was similar to calcium depletion. By the late 1970s, the clinical use of calcium channel blockers (CCBs) was widely accepted for variety of cardiovascular indications, including hypertension, dysrhythmias, and angina. Later indications, including Raynaud phenomenon, ...
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ژورنال
عنوان ژورنال: Prescriber
سال: 2007
ISSN: 0959-6682,1931-2253
DOI: 10.1002/psb.93